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Rev Electron Autopsia 2014;12(1)

Rev Electron Autopsia Vol 12, No 1 (2014)

Tabla de contenidos


Nueva etapa en la Revista Electrónica de la Autopsia: La autopsia une a la Anatomía Patológica y a la Patología Forense PDF
Joaquín S. Lucena Romero 1-3

Patología Autópsica Pediátrica

Importancia de la autopsia fetal en casos de abortos espontáneos. PDF
Tanya Kitova, Le Vinh, Borislav Kitov, Radoslav Minkov 4-7

REA/EJAutopsy en las redes sociales



Estimado lector de la Revista Electrónica de la Autopsia:


Queremos informarte que nuestra revista está presente ya en las redes sociales. Se acaba de crear una cuenta en Twitter bajo el nombre @EJAutopsy a través de la cual os enviaremos información puntual de los artículos que vayamos publicando y de otra información que pudiera ser de vuestro interés tanto sobre la autopsia clínica como forense. Ya sabes que si dispones de una cuenta en Twitter te invitamos a que nos sigas.


Además puedes encontrarnos también en Facebook.


Aprovechamos finalmente la ocasión para animaros a enviar vuestros manuscritos a la Revista Electrónica de la Autopsia. No lo dejéis para mañana. Los esperamos.

Recibe un cordial saludo
Equipo Editor de la Rev Electon Autopsia

Declaración de Dublín sobre Salud Materna

Declaración de Dublín sobre Salud Materna (Septiembre 2012)

Dublin Declaration

“Como investigadores y médicos experimentados en Ginecología y Obstetricia, afirmamos que el aborto inducido – la destrucción deliberada del no nacido – no es médicamente necesaria para salvar la vida de una mujer.

Sostenemos que existe una diferencia fundamental entre el aborto y los tratamientos necesarios que se llevan a cabo para salvar la vida de la madre, aún si aquellos tratamientos dan como resultado la pérdida de la vida del niño no nacido.

Confirmamos que la prohibición del aborto no afecta, de ninguna manera, la disponibilidad de un cuidado óptimo de la mujer embarazada.”

Si usted es un profesional médico o estudiantes de medicina, por favor Firme la Declaración!

Si quiere firmar ésta declaración, siga por favor el vínculo

Escuela de Rescate a la Madrileña

Escuela de Rescate a la Madrileña: Desde el respeto a la mujer y la voluntad firme de querer ayudarla, recluta "personas apasionadas por ayudar a mujeres en situación de vida o muerte para sus hijos".

Leer más en: HO - Jesús Poveda convoca una Escuela de Rescate, Recursos para embarazadas - Red Madre y Escuela de Rescatadores Juan Pablo II

AVISO: La línea 900 en la Comunidad de Madrid ha sido sustituida por el número Teléfono 24 h.


Ebola Hemorrhagic Fever

Outbreak of Ebola in Guinea, Liberia, and Sierra Leone

Ebola hemorrhagic fever (Ebola HF) is one of numerous Viral Hemorrhagic Fevers. It is a severe, often fatal disease in humans and nonhuman primates (such as monkeys, gorillas, and chimpanzees).

2014 Ebola Outbreak in West Africa: The Guinean Ministry of Health, the Ministry of Health and Sanitation of Sierra Leone, the Ministry of Health and Social Welfare of Liberia, and the Nigerian Ministry of Health are working with national and international partners to investigate and respond to the outbreak.

More about Ebola HF at the CDC»

Pathology Resident Wiki: Pathology Links

The Pathology Resident Wiki!
The wiki about Pathology that anyone can edit.

Pathology Links

The Human Protein Atlas

The Human Protein Atlas

Here you can search for a gene or protein and find protein expression profiles based on immunohistochemistry for a large number of human tissues, cancers and cell lines, subcellular localization in three cell lines, transcript expression levels in three cell lines or use Fields in the Search function to build your own query to find all proteins expressed in a certain organ or specific tissue, located in a certain subcellular compartment or differentially expressed in a given tumor type. Go to search examples.

Site: The Human Protein Atlas

Introduction to Linux | an edX Course

LFS101x  | Introduction to Linux

Introduction to Linux is a edX Course (follow the link)

School: LinuxFoundationX
Course Code: LFS101x
Classes Start: 1 Aug 2014
Estimated effort: Most users will find that thoroughly covering the material will take anywhere from 40 to 60 hours

Develop a good working knowledge of Linux using both the graphical interface and command line, covering the major Linux distribution families.

About this Course

Linux powers 94% of the world’s supercomputers, most of the servers powering the Internet, the majority of financial trades worldwide and a billion Android devices. In short, Linux is everywhere. It appears in many different architectures, from mainframes to server to desktop to mobile and on a staggeringly wide variety of hardware.

This course explores the various tools and techniques commonly used by Linux programmers, system administrators and end users to achieve their day-to-day work in a Linux environment. It is designed for experienced computer users who have limited or no previous exposure to Linux, whether they are working in an individual or Enterprise environment.

Upon completion of this training you should have a good working knowledge of Linux, from both a graphical and command line perspective, allowing you to easily navigate through any of the major Linux distributions. You will be able to continue your progress as either a user, system administrator or developer using the acquired skill set.

Cancers of the anal canal: diagnosis, treatment and future strategies

Cancers of the anal canal: diagnosis, treatment and future strategies

Emma Bown, Vikas Shah, Thiagarajan Sridhar, Kirsten Boyle, David Hemingway, Justin M Yeung

ABSTRACT: Anal cancer is an uncommon cancer; however, it is rising in incidence. There is confusion regarding nomenclature and the distinction between anal canal cancer and anal margin cancer. This article discusses the modern definition, etiology and staging of anal canal and anal margin cancers. Modern chemotherapy and radiotherapy regimens are discussed, in addition to modern imaging and radiotherapy techniques. Future preventative strategies and potential novel treatments are discussed.

Future Oncology, June 2014, Vol. 10, No. 8 , Pages 1427-1441
doi: 10.2217/fon.14.23

What if pathologists didn't exist?

Thursday, June 06, 2013

What if pathologists didn't exist?

Most of the world has no idea what pathologists do, short of the forensic ones who appear on T.V. in crime-related shows. Even many of our clinician colleagues don't fully understand what is involved in our work. Medical charts are typically full of verbiage indicating that, "the specimen was sent to pathology and the diagnosis came back..." as if this all happens magically in a "black box." Tissue is inserted into a machine and the diagnosis comes out the other end. Well... maybe one day but not in my (or your) lifetimes.

One of our former residents tipped me off to the link below from the Royal College of Pathologists of Australasia (RCPA). If you've never attended one of their meetings and are looking for a good reason to visit the land down under, I strongly recommend it. The RCPA decided to have a little fun with the concept of what medicine would be like without a pathologic underpinning.

The site begins with the following message:

"If Pathologists didn't exist where would the answers come from? Pathology is the study of the nature and causes of diseases. It underpins every aspect of medicine, from diagnosis to monitoring, and is vital for research. Without pathologists, any answers found would be questionable to say the least. Every medical test, a case of trial and error. Exactly the kind of words you don't want to hear when it comes to your health. Watch the videos and see for yourself."

What follows then is series of short, very well done and admittedly quite silly videos with the serious premise that without pathologists clinicians would be absolutely clueless about diagnosing disease. Much like tribal "witch doctors" they might be relegated to devising and using all sorts of impractical, irreproducible, and completely non-functional schemes to aid in diagnosis. If you need a good laugh check this out. Afterwards think about what this says about our pivotal role in medicine. If you have non-medical friends who want to know if you're a "real doctor," and they have a good sense of humor, pass this link on to them!

Posted by Stacey E. Mills, MD at 2:34 PM

Fuente: Pⁿ Blog

The Pⁿ Blog is a forum for opinions, questions, controversies, and instructive discussions across the field of pathology and its relevant subspecialties.


The Occasional Role of Low-risk Human Papillomaviruses 6, 11, 42, 44, and 70 in Anogenital Carcinoma

The Occasional Role of Low-risk Human Papillomaviruses 6, 11, 42, 44, and 70 in Anogenital Carcinoma Defined by Laser Capture Microdissection/PCR Methodology: Results From a Global Study

Guimerà, Núria; Lloveras, Belén; Lindeman, Jan; Alemany, Laia; van de Sandt, Miekel; Alejojo, Maria; Hernandez-Suarez, Gustavo; Bravo, Ignacio G.; Molijn, Anco; Jenkins, David; Cubilla, Antonio; Muñoz, Nubia; de Sanjose, Silvia; Bosch, Francesc Xavier; Quint, Wim

Abstract: Low-risk human papillomaviruses (LR-HPVs) have been associated occasionally with clinically and pathologically unusual anogenital malignancies. The relation between clinicopathologic features and any pathogenetic role of LR-HPV remains unclear. From a global study of 13,328 anogenital carcinomas, we identified 57 cases in which whole-tissue polymerase chain reaction using SPF10-LiPA25 showed single LR-HPV infection. In 43/46 (93.5%) available carcinomas, multiple polymerase chain reaction assays confirmed single detection of HPV6, 11, 42, 44, or 70 DNA. In 75% (n=32) of these, LR-HPV DNA was confirmed in tumor cells by laser capture microdissection. In 2 cases, including 1 adenocarcinoma, viral DNA was only found outside the tumor. All anogenital tumors with confirmed HPV6/11 showed a distinctive range of papillary, warty or warty-basaloid, squamous, or transitional histology with patchy or negative p16INK4a expression. HPV6-associated cervical tumors occurred at a low median age. HPV42/70 was associated with typical squamous cell carcinoma showing diffuse p16INK4a staining like high-risk HPV–related malignancies. HPV44 was found in malignant cells in 1 case. Viral taxonomy and theoretical analysis show that HPV6/11 belong to a different genus from HPV42/70 with E6/E7 gene products that would not bind pRb or p53, whereas HPV42/70 could bind pRb. Our data support the causal involvement of LR-HPVs in the carcinogenesis of <2% of anogenital malignancies of 2 distinct clinicopathologic patterns related to the genetic structure of the HPV types 6/11 and 70/42. HPV42/70 was associated with typical squamous carcinomas. Importantly all carcinomas associated with HPV6/11 globally showed verruco-papillary, well-differentiated, squamous, or transitional histology without p16INK4a expression.

Am J Surg Pathol September 2013 - Volume 37 - Issue 9 - p 1299–1310
doi: 10.1097/PAS.0b013e31828b6be4


Data Science Toolbox

Start doing data science in minutes

Data Science Toolbox

As a data scientist, you don't want to waste your time installing software. Our goal is to provide a virtual environment that will enable you to start doing data science in a matter of minutes.

As a teacher, author, or organization, making sure that your students, readers, or members have the same software installed is not straightforward. This open source project will enable you to easily create custom software and data bundles for the Data Science Toolbox.

Datasets and Tissue Pathways

Datasets and Tissue Pathways

The Royal College of Pathologist

The College's Standards and Datasets for Histopathology Reporting on Cancers and Tissue Pathways have been written to help pathologists work towards a consistent approach for the reporting of the more common cancers and to define the range of acceptable practice in handling pathology specimens. The table in their web page provides links to the cancer dataset documents and to the 'tissue pathways' for non-malignant diseases for each site. NICE has accredited the process used by The Royal College of Pathologists to produce its Cancer Datasets and Tissue Pathways guidance. Accreditation is valid for five years from July 2012 and is retrospectively applicable to documents produced using the processes described in our 2012 guidelines for writing datasets and tissue pathways. All guidance produced following the accredited process bears the NICE accreditation mark. More information on accreditation can be viewed at

Click for more information on datasets, tissue pathways and the Working Group on Cancer Services, including guidance for authors.

Fuente: Datasets and Tissue Pathways

Sida en EE.UU.

HIV in the United States – Statistics Overview – Statistics Center – HIV/AIDS.

Figure: Estimated New HIV Infections in the United States, 2010, for the Most Affected Subpopulations

CDC - HIV in the United States: At A Glance

Fast Facts

  • More than 1.1 million people in the United States are living with HIV infection, and almost 1 in 6 (15.8%) are unaware of their infection.
  • Gay, bisexual, and other men who have sex with men (MSMa), particularly young black/African American MSM, are most seriously affected by HIV.
  • By race, blacks/African Americans face the most severe burden of HIV.

Fuente: HIV in the United States: At A Glance

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