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Rev Electron Autopsia 2015;13(1)

Rev Electron Autopsia Vol 13, No 1 (2015)

Revista Electrónica de la Autopsia

Tabla de contenidos


Protocolos y Colaboraciones

Guía de Patología Autópsica PDF
Fidel Fernández Fernández, Felix P. Arce Mateos, Iván Fernández-Vega, Ignasi Galtés Vicente, Isabel Guerra Merino, Joaquín Lucena Romero, Marta Mayorga Fernández, Rita María Regojo, María Paz Suárez Mier, Nuria Terán 2-11


Cartas al Editor

Carta Abierta sobre el Síndrome del Bebé Sacudido y los Tribunales: Una Premisa Falsa y Defectuosa PDF
Marta Cohen, Lynne Wrennall, Bill Bache, Charles Pragnell 13-16


@EJAutopsy

REA/EJAutopsy en las redes sociales

Avisos

Revista Electrónica de la Autopsia


 

Estimado lector de la Revista Electrónica de la Autopsia:

 

Queremos informarte que nuestra revista está presente ya en las redes sociales. Se acaba de crear una cuenta en Twitter bajo el nombre @EJAutopsy a través de la cual os enviaremos información puntual de los artículos que vayamos publicando y de otra información que pudiera ser de vuestro interés tanto sobre la autopsia clínica como forense. Ya sabes que si dispones de una cuenta en Twitter te invitamos a que nos sigas.

URL: http://www.twitter.com/EJAutopsy

Además puedes encontrarnos también en Facebook.

URL: https://www.facebook.com/REVISTAELECTRONICAAUTOPSIA

Aprovechamos finalmente la ocasión para animaros a enviar vuestros manuscritos a la Revista Electrónica de la Autopsia. No lo dejéis para mañana. Los esperamos.

Recibe un cordial saludo
__
Equipo Editor de la Rev Electon Autopsia
mailto:rea@uninet.edu

SOS Aborto (24 horas)

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Rescatadores Juan Pablo II: Desde el respeto a la mujer y la voluntad firme de querer ayudarla, recluta "personas apasionadas por ayudar a mujeres en situación de vida o muerte para sus hijos".

Leer más en: Recursos para embarazadas - Red Madre y Escuela de Rescatadores Juan Pablo II

CDC recommends only two HPV shots for younger adolescents

Press Release

For Immediate Release: Wednesday October 19, 2016

CDC today recommended that 11- to 12-year-olds receive two doses of HPV vaccine at least six months apart rather than the previously recommended three doses to protect against cancers caused by human papillomavirus (HPV) infections. Teens and young adults who start the series later, at ages 15 through 26 years, will continue to need three doses of HPV vaccine to protect against cancer-causing HPV infection.

“Safe, effective, and long-lasting protection against HPV cancers with two visits instead of three means more Americans will be protected from cancer,” said CDC Director Tom Frieden, M.D., M.P.H. “This recommendation will make it simpler for parents to get their children protected in time.”

The Advisory Committee on Immunization Practices (ACIP) voted today to recommend a 2-dose HPV vaccine schedule for young adolescents. ACIP is a panel of experts that advises the CDC on vaccine recommendations in the United States. CDC Director Frieden approved the committee’s recommendations shortly after the vote. ACIP recommendations approved by the CDC Director become agency guidelines on the date published in the Morbidity and Mortality Weekly Report (MMWR).

CDC and ACIP made this recommendation after a thorough review of studies over several meetings. CDC and ACIP reviewed data from clinical trials showing two doses of HPV vaccine in younger adolescents (aged 9-14 years) produced an immune response similar or higher than the response in young adults (aged 16-26 years) who received three doses.

Generally, preteens receive HPV vaccine at the same time as whooping cough and meningitis vaccines. Two doses of HPV vaccine given at least six months apart at ages 11 and 12 years will provide safe, effective, and long-lasting protection against HPV cancers. Adolescents ages 13-14 are also able to receive HPV vaccination on the new 2-dose schedule.

CDC will provide guidance to parents, healthcare professionals, and insurers on the change in recommendation. On October 7, 2016, the U.S. Food and Drug Administration (FDA) approved adding a 2-dose schedule for 9-valent HPV vaccine (Gardasil® 9) for adolescents ages 9 through 14 years. CDC encourages clinicians to begin implementing the 2-dose schedule in their practice to protect their preteen patients from HPV cancers.

ACIP, CDC, FDA and partners monitor vaccines in use in the U.S. year-round. These updated recommendations are an example of using the latest available evidence to provide the best possible protection against serious diseases.

Fuente: Tweet de @CDC_Cancer

Human Papillomavirus (HPV) Vaccines

What are human papillomaviruses?
Which cancers are caused by HPV?
Who gets HPV infections?
Can HPV infections be prevented?
What HPV vaccines are available?
How do HPV vaccines work?
How effective are HPV vaccines?
Why are these vaccines important?
Why is it important for more people to be vaccinated?
How safe are the HPV vaccines?
Who should get the HPV vaccines?
Should the vaccines be given to people who are already infected with HPV?
Should women who already have cervical cell changes get the vaccines?
Do women who have been vaccinated still need to be screened for cervical cancer?
How much do these vaccines cost, and will insurance pay for it?
What research is being done on strategies to prevent HPV infection?
How can people learn more about HPV infection?

Follow the link to Cancer.gov

Fuente: Tweet de @theNCI

Los mejores comandos gnulinux

Los mejores comandos para GNU/Linux que deberías conocer

Autor: Ruben Andrés.

Usar el terminal en Ubuntu o en cualquier otra distribución GNU/Linux es uno de los grandes temores de aquellos usuarios que se inician en el descubrimiento de los sistemas operativos de software libre y abierto, que suelen estar más acostumbrados a las interfaces gráficas que a las líneas de comandos.

Sin embargo, conocer los comandos más básicos de Linux puede evitarte pasar por un laberinto de ventanas para llevar a cabo cualquier configuración o cambio en el sistema que, desde el terminal, tan solo supondría escribir algún que otro comando, siendo al final incluso más sencillo recordar el comando y hacerlo desde el terminal que aprenderse la ruta de ventanas hasta llegar a la opción que permite realizar el mismo cambio desde la interfaz gráfica.


Sigue leyendo...

HPV vaccine in cancer prevention

HPV and oral cancer

Prospective Study Links HPV Detection in the Mouth to Head and Neck Cancer

In a new study, researchers have confirmed that infection with human papillomavirus (HPV) 16 precedes the development of some head and neck cancers. Previous studies have established an association between HPV-16 infection and oropharyngeal cancer, a type of head and neck cancer. The new study is the first to do so using samples collected from participants prior to their cancer diagnoses.

The study also reported, for the first time, an association between head and neck cancer risk and infection with HPV types other than HPV 16.

Ilir Agalliu, M.D., Sc.D., and Robert D. Burk, M.D., of Albert Einstein College of Medicine in New York, and their colleagues reported the results of this prospective study January 21 in JAMA Oncology.

Fuente Tweet de @theNCI

Si 100 personas vivieran en la tierra



Siga el vínculo de la imagen.

Fuente Tweet de @fadouce

HotSpot3D

3-D View of Mutations May Identify Potential Targets for Cancer Drugs


The HotSpot3D computational tool models how gene mutations (shown as bubble-shaped clusters) may affect the structure of proteins (spiral-shaped ribbons) as well as how those proteins may interact with a drug. Credit: Washington University in St. Louis / Li Ding, Ph.D., and Feng Chen, Ph.D.

A new computational tool may help expand the known number of mutations in cancer cells that could be targeted with new or existing drugs.

Researchers recently reported that the tool, called HotSpot3D, allowed them to model how genetic mutations change the ways proteins function and interact with each other to potentially drive cancer. It also helped them identify more than 800 novel mutations that potentially could be targeted with existing drugs.

The research team that developed HotSpot3D, led by Li Ding, Ph.D., and Feng Chen, Ph.D., of Washington University in St. Louis, published results from this first large-scale testing of the computational tool June 13 in Nature Genetics.

Fuente: National Cancer Institute: Cancer currents blog

Download desde Git:hotspot3d

Publicaciones:

OpenSlide

OpenSlide is a C library that provides a simple interface to read whole-slide images (also known as virtual slides). The current version is 3.4.1, released 2015-04-20.

Python and Java bindings are also available. The Python binding includes a Deep Zoom generator and a simple web-based viewer. The Java binding includes a simple image viewer.

OpenSlide and its official language bindings are released under the terms of the GNU Lesser General Public License, version 2.1.

Download

Fuente: OpenSlide

What HPV vaccines are available?

Human Papillomavirus (HPV) Vaccines

What HPV vaccines are available?

Three vaccines are approved by the FDA to prevent HPV infection: Gardasil, Gardasil 9, and Cervarix. All three vaccines prevent infections with HPV types 16 and 18, two high-risk HPVs that cause about 70 percent of cervical cancers and an even higher percentage of some of the other HPV-associated cancers (warts (quadrivalent vaccine. Gardasil 9 prevents infection with the same four HPV types plus five additional high-risk HPV types (31, 33, 45, 52, and 58) and is therefore called a nonavalent, or 9-valent, vaccine. All three vaccines are given through a series of three injections into muscle tissue over a 6-month period.

The FDA has approved Gardasil and Gardasil 9 for use in females ages 9 through 26 for the prevention of HPV-caused cervical, vulvar, vaginal, and anal cancers; precancerous cervical, vulvar, vaginal, and anal lesions; and genital warts. Gardasil and Gardasil 9 are also approved for use in males for the prevention of HPV-caused anal cancer, precancerous anal lesions, and genital warts. Gardasil is approved for use in males ages 9 through 26, and Gardasil 9 is approved for use in males ages 9 through 15.

Females and males who have previously received Gardasil may be able to also receive Gardasil 9. FDA has information for patients about Gardasil 9 available at http://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM426460.pdf.

The Cervarix vaccine is produced by GlaxoSmithKline (GSK). It targets two HPV types—16 and 18—and is called a bivalent vaccine. The FDA has approved Cervarix for use in females ages 9 through 25 for the prevention of cervical cancer caused by HPV.

In addition to providing protection against the HPV types included in these vaccines, the vaccines have been found to provide partial protection against a few additional HPV types that can cause cancer, a phenomenon called cross-protection. The vaccines do not prevent other sexually transmitted diseases, nor do they treat existing HPV infections or HPV-caused disease.

Because currently available HPV vaccines do not protect against all HPV infections that cause cancer, it is important for vaccinated women to continue to undergo cervical cancer screening. There could be some future changes in recommendations for vaccinated women.

Fuente: Tweet de @theNCI: https://twitter.com/theNCI/status/745934456733732864?s=09

V Curso de Patología Digital


V Curso de Patología Digital

Lugar de celebración:
Oporto, Portugal
Fecha de inicio:
26 de octubre de 2016
Fecha de finalización:
28 de octubre de 2016
Más información:
El V Curso de Patología Digital, se celebra en Oporto, Portugal, los días 26 al 28 de octubre de 2016, bajo los auspicios científicos del Club de Patología Digital de la Sociedad Española de Anatomía Patológica (SEAP).
 
Gracias al entusiasmo y colaboración de los compañeros de Ipatimup (Instituto de Patologia e Imunologia Molecular e Celular da Universidade do Porto, http://www.ipatimup.pt/), esta nueva edición tendrá lugar por primera vez fuera de España, en este caso, con el fin de incrementar las ya excelentes relaciones entre patólogos portugueses y españoles y crear vínculos de colaboración entre España y Portugal. Esto permitirá demostrar de forma efectiva que la patología digital no sólo rompe barreras organizativas y tecnológicas sino que permite crear redes de profesionales de diferentes países europeos que, apoyándose en una tecnología de imagen cada vez más avanzada, son capaces de ayudarse mutuamente.
 
Otra de las novedades importantes de este año será la colaboración del proyecto Europeo AIDPATH (http://aidpath.eu/) en la organización del curso, permitiendo la participación de ponentes de primer nivel europeo
 
En el V Curso de Patología Digital se presta atención especial a los temas de calidad de la imagen digital y el análisis de imagen automatizado. También se abordarán de forma detallada los avances tecnológicos en patología digital.
 
En esta edición se mantienen los talleres prácticos, que tanto éxito tuvieron en la III edición anterior, en los que los asistentes podrán realizar ejercicios prácticos usando el ordenador, bajo la supervisión y guía del profesor del curso.
 
Estamos seguros que todos los asistentes disfrutarán del magnífico entorno que ofrece Oporto.
 

Understanding Cervical Changes: A Health Guide for Women

Most women who have abnormal cervical screening tests do not have cervical cancer. Most have early cell changes that can be monitored, since they often go away on their own – or treated early, to prevent problems later. It is important to get the follow-up visits, tests, or treatment that your health care provider advises.

You can also access the information on this page as an e-book or PDF. Use this information to help you talk with your doctor after an abnormal cervical cancer screening result. If you have additional questions about cervical cancer screening, you may contact the National Cancer Institute.

Fuente: Tweet de @theNCI: https://twitter.com/theNCI/status/740137011043045376?s=09